Linux without sighted help

[Karen Lewellen]

Slightly off from this thread, perhaps,  but I did not get an answer when I 
asked over at speakup, that I saw at least.
Which distribution has the best hardware synthesizer support just now?
I am still leaning in the Debian, Fedora arena, wanting something more 
old fashioned then the more desktop sort of thing, because on the one hand 
I will be running DOS as my main os, and on the other, I do not want to 
use my system's sound card for speech, since I have access to a hardware 
synthesizer.
Thoughts?
Karen